ABSTRACT
Oculogyric crisis which is a dystonic reaction is commonly caused by neuroleptics and rarely occurs with atypical antipsychotics specially Clozapine. In this article a case of Clozapine induced oculogyric crisis is reported. The patient was a 25-years-old woman with auditory hallucination, loosening of association and persecutory delusion that was admitted and treated. Because of poor response to typical antipsychotics, she was prescribed Clozapine. Then she experienced multiple episodes of oculogyric crisis and was treated successfully with anticholinergic medication [Artane]. In this special case, Clozapine caused oculogyric crisis. This side effect is rare but should be considered as a possible adverse effect of Clozapine. On the basis of this report, Clozapine induced oculogyric crisis may be treated successfully with Artane